| Long name: |
MLCK Primary Polyclonal Antibody |
| Also known as: |
MLCK PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MLCK |
| Specificity: |
This is a highly specific antibody against MLCK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
700-750/1914 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MLCK |
| Gene ID number: |
4638 |
| Swiss Prot: |
Q15746 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A pseudogene is located on the p arm of chromosome 3, Additional variants have been identified but lack full length transcripts, Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin, In addition, Jul 2008], This gene encodes both smooth muscle and nonmuscle isoforms, This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity, [provided by RefSeq, a muscle member of the immunoglobulin gene superfamily, a small protein identical in sequence to the C-terminus of myosin light chain kinase, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme, it encodes telokin, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments, using a separate promoter in an intron in the 3' region, This gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AAT7, Kinase-related protein, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK, MYLK1, Myosin light chain kinase, Telokin, smMLCK, smooth muscle, KRP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MLCK |
| Short name: |
MLCK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MLCK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29826 |
| Gene: |
MYLK3 |
More about : MYLK3 |
| Long gene name: |
myosin light chain kinase 3 |
| Synonyms: |
caMLCK MLCK |
| Synonyms name: |
MLC kinase |
| Locus: |
16q11, 2 |
| Discovery year: |
2008-01-23 |
| GenBank acession: |
AJ247087 |
| Entrez gene record: |
91807 |
| Pubmed identfication: |
17885681 |
| RefSeq identity: |
NM_182493 |
| Havana BLAST/BLAT: |
OTTHUMG00000132543 |