| Catalog number: | bs-3837R-Cy7 |
|---|---|
| Price: | 735 € |
| Supplier: | MBS Polyclonals_1 |
| Product name: | Hamartin/TSC1 Antibody, Cy7 Conjugated |
| Quantity: | 100ug |
| Related search: |
| Long name: | Cy7 Conjugated, Hamartin/TSC1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy7 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Hamartin/TSC1 |
| Specificity: | This is a highly specific antibody against Hamartin/TSC1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human Hamartin |
| Gene ID number: | 7248 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, TSC1 interacts with tuberin m(TSC2), The Hamartin/Tuberin complex has been shown to inhibit mTor, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1, or TSC1, suggesting a role for TSC proteins in modulation of cell adhesion and morphology, which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins, Hamartin |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 743nm/767nm |
| Synonyms: | KIAA0243 LAM hamartin |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: | Hamartin/TSC1 Conjugated |
| Short name: | Conjugated, Hamartin/TSC1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy7 |
| Alternative name: | cyanine 7 coupled, Hamartin/TSC1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 12362 |
| Gene: | TSC1 | More about : TSC1 |
| Long gene name: | tuberous sclerosis 1 |
| Synonyms gene: | TSC |
| Locus: | 9q34 |
| Discovery year: | 1986-01-01 |
| GenBank acession: | AF013168 |
| Pubmed identfication: | 9242607 10806479 |
| Havana BLAST/BLAT: | OTTHUMG00000020844 |
| Locus Specific Databases: | TSC Mutation Database Tuberous sclerosis database LRG_486 |
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