Hamartin/TSC1 Antibody, Biotin Conjugated

Catalog number:	bs-3837R-Biotin Buy Now
Price:	735 €
Supplier:	MBS Polyclonals_1
Product name:	Hamartin/TSC1 Antibody, Biotin Conjugated
Quantity:	100ug
Related search:	antibody tsc antibodies hamartintsc gene proteins sclerosis deg

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Long name:	Biotin Conjugated, Hamartin/TSC1 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Hamartin/TSC1
Specificity:	This is a highly specific antibody against Hamartin/TSC1
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from human Hamartin
Gene ID number:	7248
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, TSC1 interacts with tuberin m(TSC2), The Hamartin/Tuberin complex has been shown to inhibit mTor, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1, or TSC1, suggesting a role for TSC proteins in modulation of cell adhesion and morphology, which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins, Hamartin
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	KIAA0243 LAM hamartin
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Hamartin/TSC1 Conjugated
Short name:	Conjugated, Hamartin/TSC1 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Hamartin/TSC1 (Antibody to)
Alternative technique:	antibodies
Identity:	12362
Gene:	TSC1 | More about : TSC1
Long gene name:	tuberous sclerosis 1
Synonyms gene:	TSC
Locus:	9q34
Discovery year:	1986-01-01
GenBank acession:	AF013168
Pubmed identfication:	9242607 10806479
Havana BLAST/BLAT:	OTTHUMG00000020844
Locus Specific Databases:	TSC Mutation Database Tuberous sclerosis database LRG_486

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