Hamartin/TSC1 Antibody

Catalog number:	bs-3837R Buy Now
Price:	735 €
Supplier:	MBS Polyclonals_1
Product name:	Hamartin/TSC1 Antibody
Quantity:	100ug
Related search:	antibody tsc hamartintsc antibodies gene sclerosis synonyms

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Long name:	Hamartin/TSC1 Primary Polyclonal Antibody
Also known as:	Hamartin/TSC1 PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Hamartin/TSC1
Specificity:	This is a highly specific antibody against Hamartin/TSC1
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hamartin
Gene ID number:	7248
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, TSC1 interacts with tuberin m(TSC2), The Hamartin/Tuberin complex has been shown to inhibit mTor, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1, or TSC1, suggesting a role for TSC proteins in modulation of cell adhesion and morphology, which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins, Hamartin
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	TSC1, TSC1_HUMAN, Tuberous sclerosis 1 protein, LAM
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Hamartin/TSC1
Short name:	Hamartin/TSC1 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Hamartin/TSC1 (Antibody to)
Alternative technique:	antibodies
Identity:	12362
Gene:	TSC1 | More about : TSC1
Long gene name:	tuberous sclerosis 1
Synonyms gene:	TSC
Synonyms:	KIAA0243 LAM hamartin
Locus:	9q34
Discovery year:	1986-01-01
GenBank acession:	AF013168
Pubmed identfication:	9242607 10806479
Havana BLAST/BLAT:	OTTHUMG00000020844
Locus Specific Databases:	TSC Mutation Database Tuberous sclerosis database LRG_486

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