PHD2 Antibody, ALEXA FLUOR 350

Catalog number:	bs-3686R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	PHD2 Antibody, ALEXA FLUOR 350
Quantity:	100ul
Related search:	alexa antibody gene antibodies conjugated egl hif hypoxiainducible

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Long name:	ALEXA FLUOR 350 Conjugated, PHD2 Polyclonal Antibody
Also known as:	Anti-PHD2 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	PHD2
Specificity:	This is a highly specific antibody against PHD2
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	30-70/426
Subcellular location:	Nucleus, Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PHD2
Gene ID Number:	54583
Swiss Prot:	Q9GZT9
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Also hydroxylates HIF2A, CODD) of HIF1A, EGLN1 is the most important isozyme under normoxia and, Has a preference for the CODD site for both HIF1A and HIF1B, Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex, Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, Target proteins are preferencially recognized via a LXXLAP motif, Under hypoxic conditions, and C-terminal, and increased expression of hypoxy-inducible genes, heterodimerization with HIF1B, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality, the hydroxylation reaction is attenuated allowing HIFs to escape degradation resulting in their translocation to the nucleus, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins, through regulating the stability of HIF1, under normoxic conditions, Cellular oxygen sensor that catalyzes
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	SM-20 PHD2 ZMYND6 HIFPH2
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	PHD2
Short name:	PHD2 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, PHD2 (Antibody to)
Alternative technique:	antibodies
Identity:	1232
Gene:	EGLN1 | More about : EGLN1
Long gene name:	egl-9 family hypoxia inducible factor 1
Synonyms gene:	C1orf12
Synonyms gene name:	EGL nine (C, elegans) egl-9 family hypoxia-inducible factor 1 , elegans) homolog 1 egl nine homolog 1 (C
Synonyms name:	HIF prolyl hydroxylase 2
Locus:	1q42, 2
Discovery year:	2000-06-16
GenBank acession:	AJ310543
Entrez gene record:	54583
Pubmed identfication:	11056053
RefSeq identity:	NM_022051
Classification:	Zinc fingers MYND-type
Havana BLAST/BLAT:	OTTHUMG00000038027

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