| Long name: |
ALEXA FLUOR 647 Conjugated, SMC1 Polyclonal Antibody |
| Also known as: |
Anti-SMC1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SMC1 |
| Specificity: |
This is a highly specific antibody against SMC1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
150-200/1233 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMC1 |
| Gene ID Number: |
8243 |
| Swiss Prot: |
Q14683 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At anaphase, Central component of cohesin complex, Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint, allowing sister chromatids to segregate, or via its phosphorylation by ATR, the complex is cleaved and dissociates from chromatin, Involved in chromosome cohesion during cell cycle and in DNA repair |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
bK268H5 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SMC1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
SMC1 |
| Short name: |
SMC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, SMC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11112 |
| Gene: |
SMC1B |
More about : SMC1B |
| Long gene name: |
structural maintenance of chromosomes 1B |
| Synonyms gene: |
SMC1L2 |
| Synonyms gene name: |
SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 SMC1 structural maintenance of chromosomes 1-like 2 (yeast) |
| Locus: |
22q13, 31 |
| Discovery year: |
2000-01-12 |
| GenBank acession: |
AJ504806 |
| Entrez gene record: |
27127 |
| Pubmed identfication: |
10591208 11564881 |
| RefSeq identity: |
NM_148674 |
| Classification: |
Structural maintenance of chromosomes proteins Cohesin complex |
| Havana BLAST/BLAT: |
OTTHUMG00000151334 |