SMC1 (Ser360) Antibody, ALEXA FLUOR 555

Catalog number:	bs-3406R-A555 Buy Now
Price:	281 €
Supplier:	Bioss Primary Unconjugated Antibodies
Product name:	SMC1 (Ser360) Antibody, ALEXA FLUOR 555
Quantity:	0.1ml
Related search:	smc chromosomes ser structural maintenance protein hsmchsmc proteins nuclear metaphase

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Long name:	ALEXA FLUOR 555 Conjugated, SMC1 (Ser360) Polyclonal Antibody
Also known as:	Anti-SMC1 Ser360 PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	SMC1 Ser360
Specificity:	This is a highly specific antibody against SMC1 Ser360
Modification:	Phosphorylation
Modification Site:	Ser360
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human SMC1 around the phosphorylation site of Ser360
Gene ID Number:	8243
Tested applications:	IF(IHC-P), FCM
Recommended dilutions:	IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	A number of cellular factors interact with hSMC1/hSMC3 during cell cycle, A subset of hSMC1/hSMC3 is localized to spindle poles, DNA recombination and repair and global transcriptional repression, Human cohesion complex associates with chromosomes which peaks at S phase and dissociates from chromosomes during G2/M transition, In addition, SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells, Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase, The chromosome proteins are conserved in eukaryotes and can lead to mitotic chromosome segregation defects, The major population of hSMC1/hSMC3 is in a compex with hRAD21 forming the human cohesion complex, a subpopulation of hSMC1/hSMC3 associates tightly with nuclear matrix and centrosomes during interphase, hSMC1/hSMC3 is required for spindle aster formation in vitro and reacts with nuclear mitotic apparatus protein in vivo, including mitotic chromosome organization, spindles and kinetochores during mitosis when cohesin is in the cytoplasm, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics, Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	SMC 1, SMC1, SMC1A, SMC1A_HUMAN, SMC1B, SMC1BETA, SMC1L1, SMC1L2, SMC1alpha, SMC1alpha protein, SMC1beta protein, SMCB, Segregation of mitotic chromosomes 1, Segregation of mitotic chromosomes like 1, Structural Maintenance of Chromosomes-1 Like 1, Structural maintenance of chromosome 1 like 1 protein, Structural maintenance of chromosome 1 like 2 protein, Structural maintenance of chromosomes 1A, Structural maintenance of chromosomes 1B, structural maintenance of chromosomes 1-like 2 yeast, CDLS2
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	SMC1 (Ser360)
Short name:	SMC1 (Ser360) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, SMC1 (Ser360) (Antibody to)
Alternative technique:	antibodies

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