TAK1(Thr184) Antibody, FITC Conjugated

Catalog number:	bs-3436R-FITC Buy Now
Price:	456 €
Supplier:	fabgen
Product name:	TAK1(Thr184) Antibody, FITC Conjugated
Quantity:	100 µg
Related search:	antibody kinase antibodies conjugated gene mapk transduction fluorescent crossreactivity

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Long name:	FITC Conjugated, TAK1(Thr184) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	TAK1 Thr184
Specificity:	This phosphorylation site is homologous across the listed species, This is a highly specific antibody against TAK1 Thr184
Modification:	Phosphorylation
Modification site:	Thr184
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	160-210/605
Subcellular location:	Cell membrane, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184
Gene ID number:	6885
Swiss Prot:	O43318
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), Ceramides are also able to activate MAP3K7/TAK1, In osmotic stress signaling, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis, Mediates signal transduction of TRAF6, Once activated, Plays an important role in the cascades of cellular responses evoked by changes in the environment, Promotes TRIM5 capsid-specific restriction activity, TGFB-related factors like BMP2 and BMP4, These MAP2Ks in turn activate p38 MAPKs, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, but not that of NF-kappa-B, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK), plays a major role in the activation of MAPK8/JNK1, toll-like receptors (TLR), transforming growth factor-beta (TGFB), tumor necrosis factor receptor CD40 and B-cell receptor (BCR), various cytokines including interleukin-1 (IL-1), while nuclear factor-kappa B is activated by IKK, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	MEKK7
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	TAK1(Thr184) Conjugated
Short name:	FITC Conjugated, TAK1(Thr184) Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, TAK1(Thr184) (Antibody to)
Alternative technique:	antibodies
Identity:	6859
Gene:	MAP3K7 | More about : MAP3K7
Long gene name:	mitogen-activated protein kinase kinase kinase 7
Synonyms gene:	TAK1
Synonyms name:	TGF-beta activated kinase 1
Locus:	6q15
Discovery year:	1998-05-22
GenBank acession:	AB009356
Entrez gene record:	6885
Pubmed identfication:	9466656
RefSeq identity:	NM_145331
Classification:	Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000015217
Locus Specific Databases:	The Globin Gene Server

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