TAK1(Thr184) Antibody, Biotin Conjugated

Catalog number:	bs-3436R-Biotin Buy Now
Price:	333 €
Supplier:	adi
Product name:	TAK1(Thr184) Antibody, Biotin Conjugated
Quantity:	5 mg
Related search:	kinase antibody gene biotin mapk transduction synonyms activate

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Long name:	Biotin Conjugated, TAK1(Thr184) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	TAK1 Thr184
Specificity:	This phosphorylation site is homologous across the listed species, This is a highly specific antibody against TAK1 Thr184
Modification:	Phosphorylation
Modification site:	Thr184
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	160-210/605
Subcellular location:	Cell membrane, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184
Gene ID number:	6885
Swiss Prot:	O43318
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), Ceramides are also able to activate MAP3K7/TAK1, In osmotic stress signaling, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis, Mediates signal transduction of TRAF6, Once activated, Plays an important role in the cascades of cellular responses evoked by changes in the environment, Promotes TRIM5 capsid-specific restriction activity, TGFB-related factors like BMP2 and BMP4, These MAP2Ks in turn activate p38 MAPKs, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, but not that of NF-kappa-B, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK), plays a major role in the activation of MAPK8/JNK1, toll-like receptors (TLR), transforming growth factor-beta (TGFB), tumor necrosis factor receptor CD40 and B-cell receptor (BCR), various cytokines including interleukin-1 (IL-1), while nuclear factor-kappa B is activated by IKK, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	MEKK7
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	TAK1(Thr184) Conjugated
Short name:	Conjugated, TAK1(Thr184) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, TAK1(Thr184) (Antibody to)
Alternative technique:	antibodies
Identity:	6859
Gene:	MAP3K7 | More about : MAP3K7
Long gene name:	mitogen-activated protein kinase kinase kinase 7
Synonyms gene:	TAK1
Synonyms name:	TGF-beta activated kinase 1
Locus:	6q15
Discovery year:	1998-05-22
GenBank acession:	AB009356
Entrez gene record:	6885
Pubmed identfication:	9466656
RefSeq identity:	NM_145331
Classification:	Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000015217
Locus Specific Databases:	The Globin Gene Server

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