TAK1(Thr184) Antibody, ALEXA FLUOR 488

Catalog number:	bs-3436R-A488 Buy Now
Price:	Ask price €
Supplier:	accurate-monoclonals
Product name:	TAK1(Thr184) Antibody, ALEXA FLUOR 488
Quantity:	vial
Related search:	kinase antibody fluor gene antibodies mapk transduction synonyms signaling

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Long name:	ALEXA FLUOR 488 Conjugated, TAK1(Thr184) Polyclonal Antibody
Also known as:	Anti-TAK1 Thr184 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	TAK1 Thr184
Specificity:	This is a highly specific antibody against TAK1 Thr184
Modification:	Phosphorylation
Modification Site:	Thr184
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	160-210/605
Subcellular location:	Cell membrane, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184
Gene ID Number:	6885
Swiss Prot:	O43318
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), Ceramides are also able to activate MAP3K7/TAK1, In osmotic stress signaling, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis, Mediates signal transduction of TRAF6, Once activated, Plays an important role in the cascades of cellular responses evoked by changes in the environment, Promotes TRIM5 capsid-specific restriction activity, TGFB-related factors like BMP2 and BMP4, These MAP2Ks in turn activate p38 MAPKs, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, but not that of NF-kappa-B, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK), plays a major role in the activation of MAPK8/JNK1, toll-like receptors (TLR), transforming growth factor-beta (TGFB), tumor necrosis factor receptor CD40 and B-cell receptor (BCR), various cytokines including interleukin-1 (IL-1), while nuclear factor-kappa B is activated by IKK, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	MEKK7
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TAK1(Thr184) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	TAK1(Thr184)
Short name:	TAK1(Thr184) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, TAK1(Thr184) (Antibody to)
Alternative technique:	antibodies
Identity:	6859
Gene:	MAP3K7 | More about : MAP3K7
Long gene name:	mitogen-activated protein kinase kinase kinase 7
Synonyms gene:	TAK1
Synonyms name:	TGF-beta activated kinase 1
Locus:	6q15
Discovery year:	1998-05-22
GenBank acession:	AB009356
Entrez gene record:	6885
Pubmed identfication:	9466656
RefSeq identity:	NM_145331
Classification:	Mitogen-activated protein kinase kinase kinases
Havana BLAST/BLAT:	OTTHUMG00000015217
Locus Specific Databases:	The Globin Gene Server

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