| Catalog number: | bs-3091R-A647 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | cdc2 (Thr14) Antibody, ALEXA FLUOR 647 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 647 Conjugated, cdc2 (Thr14) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-cdc2 Thr14 PAb ALEXA FLUOR 647 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 647, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | cdc2 Thr14 |
| Specificity: | This is a highly specific antibody against cdc2 Thr14 |
| Modification: | Phosphorylation |
| Modification Site: | Thr14 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human cdc2 around the phosphorylation site of Thr14 [EG(p-T)YG] |
| Gene ID Number: | 983 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161, Cdc2 exists as a complex with both cyclin A and cyclin B, Furthermore, However, Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase, The best characterized of these associations is the Cdc2 p34 cyclin B complex, The isoform CDC2deltaT is found in breast cancer tissues, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration, plays a key role in the control of the eukaryotic cell cycle, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14, where it is required for entry into S phase and mitosis, which is required for the G2 to M phase transition, The cell division control protein cdc2 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 650nm/665nm |
| Synonyms: | CDK 1, CDK1, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, P34CDC2 |
| Properties: | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the cdc2 (Thr14) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 647, Alexa Fluor |
| Gene target: | cdc2 (Thr14) |
| Short name: | cdc2 (Thr14) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 647 |
| Alternative name: | ALEXA FLUOR 647, cdc2 (Thr14) (Antibody to) |
| Alternative technique: | antibodies |
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| bs-5277R-Cy5 | CDK2 (Thr14) Antibody, Cy5 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
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