cdc2 (Thr14) Antibody, Cy7 Conjugated

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Catalog number: bs-3091R-Cy7
Price: 281 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: cdc2 (Thr14) Antibody, Cy7 Conjugated
Quantity: 0.1ml
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More details :

Long name: Cy7 Conjugated, cdc2 (Thr14) Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy7
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: cdc2 Thr14
Specificity: This is a highly specific antibody against cdc2 Thr14
Modification: Phosphorylation
Modification site: Thr14
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human cdc2 around the phosphorylation site of Thr14 [EG(p-T)YG]
Gene ID number: 983
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161, Cdc2 exists as a complex with both cyclin A and cyclin B, Furthermore, However, Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase, The best characterized of these associations is the Cdc2 p34 cyclin B complex, The isoform CDC2deltaT is found in breast cancer tissues, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration, plays a key role in the control of the eukaryotic cell cycle, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14, where it is required for entry into S phase and mitosis, which is required for the G2 to M phase transition, The cell division control protein cdc2
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 743nm/767nm
Synonyms: CDK 1, CDK1, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, P34CDC2
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target: cdc2 (Thr14) Conjugated
Short name: Conjugated, cdc2 (Thr14) Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy7
Alternative name: cyanine 7 coupled, cdc2 (Thr14) (Antibody to)
Alternative technique: antibodies

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