| Catalog number: | bs-3091R-A488 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | cdc2 (Thr14) Antibody, ALEXA FLUOR 488 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, cdc2 (Thr14) Polyclonal Antibody |
|---|---|
| Also known as: | Anti-cdc2 Thr14 PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | cdc2 Thr14 |
| Specificity: | This is a highly specific antibody against cdc2 Thr14 |
| Modification: | Phosphorylation |
| Modification Site: | Thr14 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human cdc2 around the phosphorylation site of Thr14 [EG(p-T)YG] |
| Gene ID Number: | 983 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161, Cdc2 exists as a complex with both cyclin A and cyclin B, Furthermore, However, Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase, The best characterized of these associations is the Cdc2 p34 cyclin B complex, The isoform CDC2deltaT is found in breast cancer tissues, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration, plays a key role in the control of the eukaryotic cell cycle, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14, where it is required for entry into S phase and mitosis, which is required for the G2 to M phase transition, The cell division control protein cdc2 |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | CDK 1, CDK1, Cdc 2, Cell Divsion Cycle 2 Protein, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, P34CDC2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the cdc2 (Thr14) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | cdc2 (Thr14) |
| Short name: | cdc2 (Thr14) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, cdc2 (Thr14) (Antibody to) |
| Alternative technique: | antibodies |
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