| Long name: |
ALEXA FLUOR 647 Conjugated, CYLD (Ser418) Polyclonal Antibody |
| Also known as: |
Anti-CYLD Ser418 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CYLD Ser418 |
| Specificity: |
This is a highly specific antibody against CYLD Ser418 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser418 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
390-440/956 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human CYLD around the phosphorylation site of Ser418 |
| Gene ID Number: |
1540 |
| Swiss Prot: |
Q9NQC7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Contributes to the regulation of cell survival, Dispensable for the maturation of intrathymic natural killer cells, Has endodeubiquitinase activity, Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules, Inhibits nuclear translocation of NF-kappa-B, Negative regulator of Wnt signaling, Negatively regulates TNFRSF11A signaling and osteoclastogenesis (By similarity), Plays a role in the regulation of inflammation and the innate immune response, Plays a role in the regulation of microtubule dynamics, Plays an important role in the regulation of pathways leading to NF-kappa-B activation, Required for normal cell cycle progress and normal cytokinesis, and angiogenesis, and thereby contributes to the regulation of cell proliferation, but required for the continued survival of immature natural killer cells, cell migration, cell polarization, proliferation and differentiation via its effects on NF-kappa-B activation, via its effects on NF-kappa-B activation, Protease that specifically cleaves 'Lys-63'-linked polyubiquitin chains |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
KIAA0849 USPL2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the CYLD (Ser418) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
CYLD (Ser418) |
| Short name: |
CYLD (Ser418) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, CYLD (Ser418) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2584 |
| Gene: |
CYLD |
More about : CYLD |
| Long gene name: |
CYLD lysine 63 deubiquitinase |
| Synonyms gene: |
CYLD1 |
| Synonyms gene name: |
cylindromatosis (turban tumor syndrome) |
| Synonyms name: |
ubiquitin specific peptidase like 2 |
| Locus: |
16q12, 1 |
| Discovery year: |
1996-12-17 |
| GenBank acession: |
AB020656 |
| Entrez gene record: |
1540 |
| Pubmed identfication: |
7493027 |
| Classification: |
Ubiquitin specific peptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000173404 |
| Locus Specific Databases: |
LRG_491 |