Frizzled 5/8 Antibody, Biotin Conjugated

Catalog number:	bs-2930R-Biotin Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Frizzled 5/8 Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	frizzled antibody antibodies proteins hfz kinase

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Long name:	Biotin Conjugated, Frizzled 5/8 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Frizzled 5/8
Specificity:	This is a highly specific antibody against Frizzled 5/8
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	27-77/585
Subcellular location:	Extracellular
Source:	KLH conjugated synthetic peptide derived from human Frizzled 5
Gene ID number:	7855, 8325
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes, Coreceptor along with RYK of Wnt proteins, ESTs have been isolated from bone, Frizzled 5 has been reported to be expressed in fetal kidney, Frizzled 5 was cloned from a retina cDNA library, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Receptor for Wnt proteins, The Frizzled 5 protein is believed to be the receptor for the Wnt5A ligand, The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, and adult pancreas, and prostate libraries, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, fetal and adult liver, fetal lung, inhibition of GSK-3 kinase, liver/spleen, nuclear accumulation of beta-catenin and activation of Wnt target genes, placenta, such as WNT1, Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	FZD 5, FZD5, FZD5_HUMAN, FZD8, Frizzled homolog 5, Frizzled-5, Frizzled-8, Frizzled5, Fz 5, Fz-5, Fz-8, Fz5, FzE 5, FzE5, HFZ 5, Seven transmembrane receptor frizzled 5, Wnt receptor, hFz5, hFz8, C2orf31
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Frizzled 5/8 Conjugated
Short name:	Conjugated, Frizzled 5/8 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Frizzled 5/8 (Antibody to)
Alternative technique:	antibodies

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