Frizzled 5/8 Antibody, ALEXA FLUOR 350

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Catalog number: bs-2930R-A350
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: Frizzled 5/8 Antibody, ALEXA FLUOR 350
Quantity: 100ul
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Long name: ALEXA FLUOR 350 Conjugated, Frizzled 5/8 Polyclonal Antibody
Also known as: Anti-Frizzled 5/8 PAb ALEXA FLUOR 350
Category: Conjugated Primary Antibodies
Conjugated with: 350, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: Frizzled 5/8
Specificity: This is a highly specific antibody against Frizzled 5/8
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 27-77/585
Subcellular location: Extracellular
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 5
Gene ID Number: 7855, 8325
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes, Coreceptor along with RYK of Wnt proteins, ESTs have been isolated from bone, Frizzled 5 has been reported to be expressed in fetal kidney, Frizzled 5 was cloned from a retina cDNA library, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Receptor for Wnt proteins, The Frizzled 5 protein is believed to be the receptor for the Wnt5A ligand, The beta-catenin canonical signaling pathway leads to the activation of disheveled proteins, and adult pancreas, and prostate libraries, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, fetal and adult liver, fetal lung, inhibition of GSK-3 kinase, liver/spleen, nuclear accumulation of beta-catenin and activation of Wnt target genes, placenta, such as WNT1, Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 343nm/442nm
Synonyms: FZD 5, FZD5, FZD5_HUMAN, FZD8, Frizzled homolog 5, Frizzled-5, Frizzled-8, Frizzled5, Fz 5, Fz-5, Fz-8, Fz5, FzE 5, FzE5, HFZ 5, Seven transmembrane receptor frizzled 5, Wnt receptor, hFz5, hFz8, C2orf31
Properties: ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 350, Alexa Fluor
Gene target: Frizzled 5/8
Short name: Frizzled 5/8 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 350
Alternative name: ALEXA FLUOR 350, Frizzled 5/8 (Antibody to)
Alternative technique: antibodies

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