| Long name: |
ALEXA FLUOR 350 Conjugated, Frizzled 9/CD349 Polyclonal Antibody |
| Also known as: |
Anti-Frizzled 9/CD349 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Frizzled 9/CD349 |
| Specificity: |
This is a highly specific antibody against Frizzled 9/CD349 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-229/591 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 9/CD349 |
| Gene ID Number: |
8326 |
| Swiss Prot: |
O00144 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
FZD3 CD349 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Frizzled 9/CD349 |
| Short name: |
Frizzled 9/CD349 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Frizzled 9/CD349 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4047 |
| Gene: |
FZD9 |
More about : FZD9 |
| Long gene name: |
frizzled class receptor 9 |
| Synonyms gene name: |
frizzled (Drosophila) homolog 9 frizzled homolog 9 (Drosophila) frizzled 9, seven transmembrane spanning receptor frizzled family receptor 9 |
| Locus: |
7q11, 23 |
| Discovery year: |
1998-09-17 |
| GenBank acession: |
U82169 |
| Entrez gene record: |
8326 |
| Pubmed identfication: |
9147651 10198163 |
| Classification: |
Class F frizzled CD molecules , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000023051 |