| Catalog number: | bs-13239R-A555 |
|---|---|
| Price: | 265 € |
| Supplier: | MBS Polyclonals |
| Product name: | FZD3/Frizzled 3 Antibody, ALEXA FLUOR 555 |
| Quantity: | 0.06 ml |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, FZD3/Frizzled 3 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-FZD3/Frizzled 3 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | FZD3/Frizzled 3 |
| Specificity: | This is a highly specific antibody against FZD3/Frizzled 3 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 150-200/666 |
| Subcellular location: | Extracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3 |
| Gene ID Number: | 7976 |
| Swiss Prot: | Q9NPG1 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | FZD3/Frizzled 3 |
| Short name: | FZD3/Frizzled 3 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, FZD3/Frizzled 3 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4041 |
| Gene: | FZD3 | More about : FZD3 |
| Long gene name: | frizzled class receptor 3 |
| Synonyms gene name: | frizzled (Drosophila) homolog 3 frizzled homolog 3 (Drosophila) frizzled 3, seven transmembrane spanning receptor frizzled family receptor 3 |
| Locus: | 8p21, 1 |
| Discovery year: | 1998-09-17 |
| GenBank acession: | AJ272427 |
| Entrez gene record: | 7976 |
| Pubmed identfication: | 10777673 10873558 |
| RefSeq identity: | NM_145866 |
| Classification: | Class F frizzled , G protein-coupled receptors |
| Havana BLAST/BLAT: | OTTHUMG00000102145 |
| MBS611058 | Fz5 (FZD5, Frizzled Homolog 5 (Drosophila), C2orf31, Chromosome 2 Open Reading Frame 31, DKFZp434E2135, DKFZP434E2135, Frizzled-5, Frizzled 5 precursor, Frizzled-5 precursor, Fz-5, FzE5, hFz5, Hfz5, HFZ5, MGC129692, Uncharacterized Protein C2orf31) Antibody | 200ug | 614 € | MBS Polyclonals_1 | drosophila |
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