PCNA (Tyr211) Antibody, ALEXA FLUOR 350

Catalog number:	bs-2215R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	PCNA (Tyr211) Antibody, ALEXA FLUOR 350
Quantity:	100ul
Related search:	pcna alexa dna fluor antibody antibodies gene replication damage term

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Long name:	ALEXA FLUOR 350 Conjugated, PCNA (Tyr211) Polyclonal Antibody
Also known as:	Anti-PCNA Tyr211 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	PCNA Tyr211
Specificity:	This is a highly specific antibody against PCNA Tyr211
Modification:	Phosphorylation
Modification Site:	Tyr211
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	190-230/261
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from human PCNA around the phosphorylation site of Tyr211
Gene ID Number:	5111
Swiss Prot:	P12004
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	APEX2 activities, Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, Has to be loaded onto DNA in order to be able to stimulate APEX2, Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways, but not apurinic-apyrimidinic (AP) endonuclease, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion, Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	PCNA (Tyr211)
Short name:	PCNA (Tyr211) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, PCNA (Tyr211) (Antibody to)
Alternative technique:	antibodies
Identity:	8729
Gene:	PCNA | More about : PCNA
Long gene name:	proliferating cell nuclear antigen
Locus:	20p12, 3
Discovery year:	1990-01-15
GenBank acession:	J04718
Entrez gene record:	5111
Pubmed identfication:	2565339
Havana BLAST/BLAT:	OTTHUMG00000031798

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