PCNA (Tyr211) Antibody

Catalog number:	bs-2215R Buy Now
Price:	703 €
Supplier:	acr
Product name:	PCNA (Tyr211) Antibody
Quantity:	0,1 mg
Related search:	pcna dna antibodies gene replication proliferating

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Long name:	PCNA (Tyr211) Primary Polyclonal Antibody
Also known as:	PCNA (Tyr211) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	PCNA Tyr211
Specificity:	This is a highly specific antibody against PCNA Tyr211
Modification(s):	Phosphorylation
Modification site(s):	Tyr211
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	190-230/261
Subcellular location:	Nucleus
Source:	KLH conjugated synthetic phosphopeptide derived from human PCNA around the phosphorylation site of Tyr211
Gene ID number:	5111
Swiss Prot:	P12004
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	APEX2 activities, Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, Has to be loaded onto DNA in order to be able to stimulate APEX2, Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways, but not apurinic-apyrimidinic (AP) endonuclease, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion, Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	Cyclin, PCNA, Proliferating cell nuclear antigen, ATLD2
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	PCNA (Tyr211)
Short name:	PCNA (Tyr211) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	PCNA (Tyr211) (Antibody to)
Alternative technique:	antibodies
Identity:	8729
Gene:	PCNA | More about : PCNA
Long gene name:	proliferating cell nuclear antigen
Locus:	20p12, 3
Discovery year:	1990-01-15
GenBank acession:	J04718
Entrez gene record:	5111
Pubmed identfication:	2565339
Havana BLAST/BLAT:	OTTHUMG00000031798

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