| Long name: |
ALEXA FLUOR 555 Conjugated, Polycystin 2 Polyclonal Antibody |
| Also known as: |
Anti-Polycystin 2 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Polycystin 2 |
| Specificity: |
This is a highly specific antibody against Polycystin 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
680-720/968 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Polycystin 2 |
| Gene ID Number: |
5311 |
| Swiss Prot: |
Q13563 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a regulator of cilium length, Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity), PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040), leads to cilium shortening and thus decreases flow-induced signaling, together with PKD1, which decreases intracellular cAMP, Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
KIAA1879 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Polycystin 2 |
| Short name: |
Polycystin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Polycystin 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21715 |
| Gene: |
PKD1L2 |
More about : PKD1L2 |
| Long gene name: |
polycystin 1 like 2 (gene/pseudogene) |
| Synonyms gene name: |
polycystic kidney disease 1-like 2 |
| Locus: |
16q23, 2 |
| Discovery year: |
2003-08-05 |
| GenBank acession: |
AY164483 |
| Entrez gene record: |
114780 |
| Pubmed identfication: |
12782129 |
| Classification: |
C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166126 |