Polycystin 2 Antibody, ALEXA FLUOR 488

Catalog number:	bs-2158R-A488 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Polycystin 2 Antibody, ALEXA FLUOR 488
Quantity:	0.1ml
Related search:	antibody polycystin fluor cilium gene conjugated primary signaling deg

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Long name:	ALEXA FLUOR 488 Conjugated, Polycystin 2 Polyclonal Antibody
Also known as:	Anti-Polycystin 2 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Polycystin 2
Specificity:	This is a highly specific antibody against Polycystin 2
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	680-720/968
Subcellular location:	Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Polycystin 2
Gene ID Number:	5311
Swiss Prot:	Q13563
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Acts as a regulator of cilium length, Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD1L1 in cilia to facilitate flow detection in left/right patterning (By similarity), PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis, The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling, Together with TRPV4, forms mechano- and thermosensitive channels in cilium (PubMed:18695040), leads to cilium shortening and thus decreases flow-induced signaling, together with PKD1, which decreases intracellular cAMP, Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	KIAA1879
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Polycystin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Polycystin 2
Short name:	Polycystin 2 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Polycystin 2 (Antibody to)
Alternative technique:	antibodies
Identity:	21715
Gene:	PKD1L2 | More about : PKD1L2
Long gene name:	polycystin 1 like 2 (gene/pseudogene)
Synonyms gene name:	polycystic kidney disease 1-like 2
Locus:	16q23, 2
Discovery year:	2003-08-05
GenBank acession:	AY164483
Entrez gene record:	114780
Pubmed identfication:	12782129
Classification:	C-type lectin domain containing
Havana BLAST/BLAT:	OTTHUMG00000166126

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