YB1 Antibody, FITC Conjugated

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Catalog number: bs-1943R-FITC
Price: 333 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: YB1 Antibody, FITC Conjugated
Quantity: 0.1ml
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Long name: FITC Conjugated, YB1 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Anti-FITC Antibody
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: YB1
Specificity: This is a highly specific antibody against YB1
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 120-170/324
Subcellular location: Nucleus, Secreted, Cytoplasm
Source: KLH conjugated synthetic peptide derived from human YBX-1
Gene ID number: 4904
Swiss Prot: P67809
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 494nm/518nm
Properties: Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: YB1 Conjugated
Short name: FITC Conjugated, YB1 Antibody
Technique: Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: FITC
Alternative name: fluorecein coupled, YB1 (Antibody to)
Alternative technique: antibodies
Identity: 8014
Gene: YBX1 | More about : YBX1
Long gene name: Y-box binding protein 1
Synonyms gene: NSEP1
Synonyms gene name: nuclease sensitive element binding protein 1
Locus: 1p34, 2
Discovery year: 1993-10-20
GenBank acession: BC013838
Entrez gene record: 4904
Pubmed identfication: 1891370 3174636
RefSeq identity: NM_004559
Classification: Y box binding proteins
Havana BLAST/BLAT: OTTHUMG00000007523

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