YB1 Antibody

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Catalog number: bs-1943R
Price: 263 €
Supplier: Bioss Primary Unconjugated Antibodies
Product name: YB1 Antibody
Quantity: 0.1ml
Other quantities: 0.1mg 389€ 100ug 1033€
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Long name: YB1 Primary Polyclonal Antibody
Also known as: YB1 PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: YB1
Specificity: This is a highly specific antibody against YB1
Modification(s): None
Modification site(s): Unmodified antibody
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 120-170/324
Subcellular location: Nucleus, Secreted, Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YBX-1
Gene ID number: 4904
Swiss Prot: P67809
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: BP-8, CBF-A, CCAAT-binding transcription factor I subunit A, CSDA2, CSDB, DBPB, DNA-binding protein B, EFI-A, Enhancer factor I subunit A, MDR-NF1, NSEP-1, NSEP1, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, YB1
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: YB1
Short name: YB1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: YB1 (Antibody to)
Alternative technique: antibodies
Identity: 8014
Gene: YBX1 | More about : YBX1
Long gene name: Y-box binding protein 1
Synonyms gene: NSEP1
Synonyms gene name: nuclease sensitive element binding protein 1
Synonyms: YB-1 YB1 DBPB NSEP-1 MDR-NF1 BP-8 CSDB CSDA2
Locus: 1p34, 2
Discovery year: 1993-10-20
GenBank acession: BC013838
Entrez gene record: 4904
Pubmed identfication: 1891370 3174636
RefSeq identity: NM_004559
Classification: Y box binding proteins
Havana BLAST/BLAT: OTTHUMG00000007523

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