YB1 Antibody, ALEXA FLUOR 647

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Catalog number: bs-1943R-A647
Price: 332 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: YB1 Antibody, ALEXA FLUOR 647
Quantity: 100ul
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Long name: ALEXA FLUOR 647 Conjugated, YB1 Polyclonal Antibody
Also known as: Anti-YB1 PAb ALEXA FLUOR 647
Category: Conjugated Primary Antibodies
Conjugated with: 647, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: YB1
Specificity: This is a highly specific antibody against YB1
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen range: 120-170/324
Subcellular location: Nucleus, Secreted, Cytoplasm
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human YBX-1
Gene ID Number: 4904
Swiss Prot: P67809
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Binds and stabilizes cytoplasmic mRNA, Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro, Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), Binds to splice sites in pre-mRNA and regulates splice site selection, Component of the CRD-mediated complex that promotes MYC mRNA stability, Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity), Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7', May play a role in DNA repair, Promotes separation of DNA strands that contain mismatches or are modified by cisplatin, Regulates the transcription of numerous genes, The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation, such as MDR1 and HLA class II genes, Mediates pre-mRNA alternative splicing regulation
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 650nm/665nm
Properties: ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the YB1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 647, Alexa Fluor
Gene target: YB1
Short name: YB1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 647
Alternative name: ALEXA FLUOR 647, YB1 (Antibody to)
Alternative technique: antibodies
Identity: 8014
Gene: YBX1 | More about : YBX1
Long gene name: Y-box binding protein 1
Synonyms gene: NSEP1
Synonyms gene name: nuclease sensitive element binding protein 1
Locus: 1p34, 2
Discovery year: 1993-10-20
GenBank acession: BC013838
Entrez gene record: 4904
Pubmed identfication: 1891370 3174636
RefSeq identity: NM_004559
Classification: Y box binding proteins
Havana BLAST/BLAT: OTTHUMG00000007523

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