| Catalog number: | bs-13661R-Cy5 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | SLP76 Antibody, Cy5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5 Conjugated, SLP76 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | SLP76 |
| Specificity: | This is a highly specific antibody against SLP76 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human SLP76 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Although SLP-76 does not contain a motif that would indicate it to be a member of the tyrosine, However, Overexpression of Vav or SLP-76 in Jurkat cells leads to NFAT activation and IL-2 production, The discovery of SLP-76 represents an important step in elucidating the mechanism of Vav transformation and TCR-mediated NFAT activation, Vav and SLP-76 synergize to induce a robust basal and TCR-mediated IL-2 response, Vav contains a single SH2 domain that is required for its association with the T cell receptor (TCR), When co-expressed, it does contain several putative SH2/SH3-binding domains and has been shown to physically associate with the adapter protein GRB2 as well as PLC g1, serine/threonine or lipid kinase families, the biochemical basis of Vavâ, &euro, &trade, The translational product of the Vav proto-oncogene is exclusively expressed in cells of hematopoietic origin and is critical for lymphocyte development and activation, s function is unclear |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 625, 650nm/670nm |
| Synonyms: | SLP-76 |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | SLP76 Conjugated |
| Short name: | Conjugated, SLP76 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy5 |
| Alternative name: | cyanine 5 coupled, SLP76 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 6529 |
| Gene: | LCP2 | More about : LCP2 |
| Long gene name: | lymphocyte cytosolic protein 2 |
| Synonyms gene: | SLP76 |
| Synonyms gene name: | lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| Synonyms name: | 76 kDa tyrosine phosphoprotein SH2 domain-containing leukocyte protein of 76kD |
| Locus: | 5q35, 1 |
| Discovery year: | 1996-03-12 |
| Entrez gene record: | 3937 |
| Pubmed identfication: | 7706237 |
| RefSeq identity: | NM_005565 |
| Classification: | SH2 domain containing |
| Havana BLAST/BLAT: | OTTHUMG00000163121 |
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