Guanylyl Cyclase alpha 2 Antibody

Catalog number:	bs-13545R Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Guanylyl Cyclase alpha 2 Antibody
Quantity:	0.1ml
Related search:	antibody cyclase alpha guanylyl antibodies subunit the guanylate

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Long name:	Guanylyl Cyclase alpha 2 Antibody
Also known as:	Guanylyl Cyclase alpha 2 Antibody
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Guanylyl Cyclase alpha 2
Specificity:	This is a highly specific antibody against Guanylyl Cyclase alpha 2
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 2
Gene ID number:	2977
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both alpha and beta subunits are required for cGMP generation, GCS is a cGMP-synthesizing enzyme, GCS is a heme-containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, The heme moeity mediates NO activation, The membrane-bound receptor form, The soluble form, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, act as receptors for nitric oxide (NO), and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and this heme group also binds carbon monoxide (CO), are peptide hormone receptors, consisting of one alpha subunit and one beta subunit, known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which is the major receptor for the neurotransmitter nitric oxide, which weakly stimulates the enzyme, with predominant expression in kidney and liver, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	GCS-alpha 2, GCYA2_HUMAN, GUC1A2, GUCSA2, GC SA2
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Guanylyl Cyclase alpha 2
Short name:	Guanylyl Cyclase alpha 2 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Guanylyl Cyclase a 2 (Antibody to)
Alternative technique:	antibodies

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