| Catalog number: | bs-13545R-A594 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | Guanylyl Cyclase alpha 2 Antibody, ALEXA FLUOR 594 |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, Guanylyl Cyclase alpha 2 Antibody |
|---|---|
| Also known as: | Anti-Guanylyl Cyclase alpha 2 PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Guanylyl Cyclase alpha 2 |
| Specificity: | This is a highly specific antibody against Guanylyl Cyclase alpha 2 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 2 |
| Gene ID Number: | 2977 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both alpha and beta subunits are required for cGMP generation, GCS is a cGMP-synthesizing enzyme, GCS is a heme-containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, The heme moeity mediates NO activation, The membrane-bound receptor form, The soluble form, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, act as receptors for nitric oxide (NO), and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and this heme group also binds carbon monoxide (CO), are peptide hormone receptors, consisting of one alpha subunit and one beta subunit, known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which is the major receptor for the neurotransmitter nitric oxide, which weakly stimulates the enzyme, with predominant expression in kidney and liver, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | GCS-alpha 2, GCYA2_HUMAN, GUC1A2, GUCSA2, GC SA2 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | Guanylyl Cyclase alpha 2 |
| Short name: | Guanylyl Cyclase alpha 2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, Guanylyl Cyclase a 2 (Antibody to) |
| Alternative technique: | antibodies |
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