Guanylyl Cyclase alpha 1 Antibody

Catalog number:	bs-13544R Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Guanylyl Cyclase alpha 1 Antibody
Quantity:	0.1ml
Related search:	cyclase antibody alpha guanylyl antibodies subunit guanylate receptor

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Long name:	Guanylyl Cyclase alpha 1 Antibody
Also known as:	Guanylyl Cyclase alpha 1 Antibody
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Guanylyl Cyclase alpha 1
Specificity:	This is a highly specific antibody against Guanylyl Cyclase alpha 1
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	330-380/690
Subcellular location:	Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1
Gene ID number:	2982
Swiss Prot:	Q02108
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both the alpha and beta subunits are required for cGMP generation, GCS, GCS is a heme containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The heme moeity mediates NO activation, The membrane-bound receptor forms, The soluble forms, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, a cGMP-synthesizing enzyme, act as receptors for nitric oxide, and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and one beta subunit, and this heme group also binds carbon monoxide, are peptide hormone receptors, consisting of one alpha subunit, designated GCS-alpha-1, is the major receptor for the neurotransmitter nitric oxide (NO), known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which weakly stimulates the enzyme, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	GC-SA3, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3, Guanylate cyclase soluble subunit alpha-3, MYMY6, Soluble guanylate cyclase large subunit, GUCA3
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Guanylyl Cyclase alpha 1
Short name:	Guanylyl Cyclase alpha 1 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Guanylyl Cyclase a 1 (Antibody to)
Alternative technique:	antibodies

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