| Long name: |
Cy5 Conjugated, Guanylyl Cyclase alpha 1 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Guanylyl Cyclase alpha 1 |
| Specificity: |
This is a highly specific antibody against Guanylyl Cyclase alpha 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
330-380/690 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Guanylyl Cyclase alpha 1 |
| Gene ID number: |
2982 |
| Swiss Prot: |
Q02108 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, Both the alpha and beta subunits are required for cGMP generation, GCS, GCS is a heme containing heterodimer, Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, It plays a crucial role in smooth muscle contractility, The heme moeity mediates NO activation, The membrane-bound receptor forms, The soluble forms, There are two forms of guanylate cyclase, YC-1, YC-1 can also stimulate GCS in a NO-independent manner, a cGMP-synthesizing enzyme, act as receptors for nitric oxide, and at least two isoforms exist for each subunit, and both display similar enzymatic activity, and one beta subunit, and this heme group also binds carbon monoxide, are peptide hormone receptors, consisting of one alpha subunit, designated GCS-alpha-1, is the major receptor for the neurotransmitter nitric oxide (NO), known as GC, known as GCS or sGC, platelet reactivity and neurotransmission, which weakly stimulates the enzyme, Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
GC-SA3, GCS-alpha-1, GCS-alpha-3, GUC1A3, GUCSA3, GUCY1A1, GUCY1A3, Guanylate cyclase soluble subunit alpha-3, MYMY6, Soluble guanylate cyclase large subunit, GUCA3 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Guanylyl Cyclase alpha 1 Conjugated |
| Short name: |
Conjugated, Guanylyl Cyclase alpha 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, Guanylyl Cyclase a 1 (Antibody to) |
| Alternative technique: |
antibodies |