| Long name: |
FITC Conjugated, Glucose 6 phosphatase 2/IGRP Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glucose 6 phosphatase 2/IGRP |
| Specificity: |
This is a highly specific antibody against Glucose 6 phosphatase 2/IGRP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP |
| Gene ID number: |
57818 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
G6Pase localizes to the endoplasmic reticulum, G6Pase-alpha, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects, Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), Structurally, The exact catalytic acivity of IGRP is not defined, a homolog of the catalytic subunit of G6Pase, a second form, and intestine are the only tissues that express the first identified isoform, and while liver, contributes to blood glucose homeostasis in a wider range of tissues, designated G6Pase-â, is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis, kidney, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides, &circ, «, Glucose-6-phosphatase (G6Pase) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
IGRP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Glucose 6 phosphatase 2/IGRP Conjugated |
| Short name: |
FITC Conjugated, Glucose 6 phosphatase 2/IGRP Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Glucose 6 phosphatase 2/IGRP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28906 |
| Gene: |
G6PC2 |
More about : G6PC2 |
| Long gene name: |
glucose-6-phosphatase catalytic subunit 2 |
| Synonyms gene name: |
2 , catalytic, glucose-6-phosphatase |
| Synonyms name: |
islet specific glucose 6 phosphatase catalytic subunit related protein |
| Locus: |
2q31, 1 |
| Discovery year: |
2004-03-29 |
| GenBank acession: |
AF283575 |
| Entrez gene record: |
57818 |
| Pubmed identfication: |
10078553 10078554 |
| RefSeq identity: |
NM_021176 |
| Classification: |
Glucose 6-phosphatases, catalytic |
| Havana BLAST/BLAT: |
OTTHUMG00000132182 |