| Long name: |
ALEXA FLUOR 350 Conjugated, Glucose 6 phosphatase 2/IGRP Antibody |
| Also known as: |
Anti-Glucose 6 phosphatase 2/IGRP PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glucose 6 phosphatase 2/IGRP |
| Specificity: |
This is a highly specific antibody against Glucose 6 phosphatase 2/IGRP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP |
| Gene ID Number: |
57818 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
G6Pase localizes to the endoplasmic reticulum, G6Pase-alpha, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects, Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), Structurally, The exact catalytic acivity of IGRP is not defined, a homolog of the catalytic subunit of G6Pase, a second form, and intestine are the only tissues that express the first identified isoform, and while liver, contributes to blood glucose homeostasis in a wider range of tissues, designated G6Pase-â, is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis, kidney, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides, &circ, «, Glucose-6-phosphatase (G6Pase) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
IGRP |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Glucose 6 phosphatase 2/IGRP |
| Short name: |
Glucose 6 phosphatase 2/IGRP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Glucose 6 phosphatase 2/IGRP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28906 |
| Gene: |
G6PC2 |
More about : G6PC2 |
| Long gene name: |
glucose-6-phosphatase catalytic subunit 2 |
| Synonyms gene name: |
2 , catalytic, glucose-6-phosphatase |
| Synonyms name: |
islet specific glucose 6 phosphatase catalytic subunit related protein |
| Locus: |
2q31, 1 |
| Discovery year: |
2004-03-29 |
| GenBank acession: |
AF283575 |
| Entrez gene record: |
57818 |
| Pubmed identfication: |
10078553 10078554 |
| RefSeq identity: |
NM_021176 |
| Classification: |
Glucose 6-phosphatases, catalytic |
| Havana BLAST/BLAT: |
OTTHUMG00000132182 |