| Long name: |
Cy3 Conjugated, Glucose 6 phosphatase 2/IGRP Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glucose 6 phosphatase 2/IGRP |
| Specificity: |
This is a highly specific antibody against Glucose 6 phosphatase 2/IGRP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP |
| Gene ID number: |
57818 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
G6Pase localizes to the endoplasmic reticulum, G6Pase-alpha, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects, Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), Structurally, The exact catalytic acivity of IGRP is not defined, a homolog of the catalytic subunit of G6Pase, a second form, and intestine are the only tissues that express the first identified isoform, and while liver, contributes to blood glucose homeostasis in a wider range of tissues, designated G6Pase-â, is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis, kidney, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides, &circ, «, Glucose-6-phosphatase (G6Pase) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
IGRP |
| Properties: |
1 of the Glucose 6 phosphatase 2/IGRP Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Glucose 6 phosphatase 2/IGRP Conjugated |
| Short name: |
Conjugated, Glucose 6 phosphatase 2/IGRP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Glucose 6 phosphatase 2/IGRP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
28906 |
| Gene: |
G6PC2 |
More about : G6PC2 |
| Long gene name: |
glucose-6-phosphatase catalytic subunit 2 |
| Synonyms gene name: |
2 , catalytic, glucose-6-phosphatase |
| Synonyms name: |
islet specific glucose 6 phosphatase catalytic subunit related protein |
| Locus: |
2q31, 1 |
| Discovery year: |
2004-03-29 |
| GenBank acession: |
AF283575 |
| Entrez gene record: |
57818 |
| Pubmed identfication: |
10078553 10078554 |
| RefSeq identity: |
NM_021176 |
| Classification: |
Glucose 6-phosphatases, catalytic |
| Havana BLAST/BLAT: |
OTTHUMG00000132182 |