| Long name: |
ALEXA FLUOR 647 Conjugated, Notch1/MOTC Polyclonal Antibody |
| Also known as: |
Anti-Notch1/MOTC PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Notch1/MOTC |
| Specificity: |
This is a highly specific antibody against Notch1/MOTC |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
2150-2200/2555 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch1 |
| Gene ID Number: |
4851 |
| Swiss Prot: |
P46531 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Affects the implementation of differentiation, During cerebellar development, Important for follicular differentiation and possibly cell fate selection within the follicle, Involved in angiogenesis, Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO), Involved in the maturation of both CD4+ and CD8+ cells in the thymus, Jagged2 and Delta1 to regulate cell-fate determination, May be involved in mesoderm development, May enhance HIF1A function by sequestering HIF1AN away from HIF1A, May play an essential role in postimplantation development, Represses neuronal and myogenic differentiation, Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting, probably in some aspect of cell specification and/or differentiation, proliferation and apoptotic programs, somite formation and neurogenesis, Functions as a receptor for membrane-bound ligands Jagged1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AOS5, AOVD1, NOTCH1, Neurogenic locus notch homolog protein 1, Notch 1, TAN1, Translocation-associated notch protein TAN-1, hN1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Notch1/MOTC Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Notch1/MOTC |
| Short name: |
Notch1/MOTC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, notch 1/MOTC (Antibody to) |
| Alternative technique: |
antibodies |