Notch1/MOTC Antibody

Catalog number:	bs-1335R Buy Now
Price:	333 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Notch1/MOTC Antibody
Quantity:	0.1ml
Related search:	antibody notch antibodies involved storage

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Long name:	Notch1/MOTC Primary Polyclonal Antibody
Also known as:	Notch1/MOTC PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Notch1/MOTC
Specificity:	This is a highly specific antibody against Notch1/MOTC
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	2150-2200/2555
Subcellular location:	Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch1
Gene ID number:	4851
Swiss Prot:	P46531
Tested Applications:	IF(IHC-P), IHC-P
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Affects the implementation of differentiation, During cerebellar development, Important for follicular differentiation and possibly cell fate selection within the follicle, Involved in angiogenesis, Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO), Involved in the maturation of both CD4+ and CD8+ cells in the thymus, Jagged2 and Delta1 to regulate cell-fate determination, May be involved in mesoderm development, May enhance HIF1A function by sequestering HIF1AN away from HIF1A, May play an essential role in postimplantation development, Represses neuronal and myogenic differentiation, Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting, probably in some aspect of cell specification and/or differentiation, proliferation and apoptotic programs, somite formation and neurogenesis, Functions as a receptor for membrane-bound ligands Jagged1
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	AOS5, AOVD1, NOTCH1, Neurogenic locus notch homolog protein 1, Notch 1, TAN1, Translocation-associated notch protein TAN-1, hN1
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Notch1/MOTC
Short name:	Notch1/MOTC Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	notch 1/MOTC (Antibody to)
Alternative technique:	antibodies

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