| Long name: |
FITC Conjugated, GEM Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GEM |
| Specificity: |
This is a highly specific antibody against GEM |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GEM |
| Gene ID number: |
2669 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Ectopic Gem expression is sufficient to stimulate cell flattening and neurite extension in N1E-115 and SH-SY5Y neuroblastoma cells, Gem was also observed in developing trigeminal nerve ganglia in 12, High intracellular Gem levels, Rad and Gem bind calmodulin in a Ca2+-dependent manner via this C-terminal extension, The human Gem gene maps to chromosome &, The interaction of Gem with beta-subunits regulates Ca2+ channel expression at the cell surface, demonstrating that Gem expression is a property of normal ganglionic development, involving residues 278â, promote profound changes in cell morphology, suggesting a role for Gem in cytoskeletal rearrangement and/or morphological differentiation of neurons, which interact with intact microtubules and microfilaments, which lack typical C-terminal amino acid motifs for isoprenylation, #65279, &euro, &ldquo, 1, 297 in human Rad, 5 day mouse embryos, 8q22, Gem belongs to the Rad/Gem/Kir (RGK) subfamily of Ras-related GTPases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIR |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GEM Conjugated |
| Short name: |
FITC Conjugated, GEM Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GEM (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4234 |
| Gene: |
GEM |
More about : GEM |
| Long gene name: |
GTP binding protein overexpressed in skeletal muscle |
| Synonyms gene name: |
GTP-binding protein overexpressed in skeletal muscle |
| Synonyms name: |
kinase-inducible Ras-like protein |
| Locus: |
8q22, 1 |
| Discovery year: |
1995-08-15 |
| Entrez gene record: |
2669 |
| Pubmed identfication: |
7912851 11956230 |
| RefSeq identity: |
NM_181702 |
| Classification: |
RGK type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000164392 |