| Long name: |
Biotin Conjugated, GEM Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GEM |
| Specificity: |
This is a highly specific antibody against GEM |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GEM |
| Gene ID number: |
2669 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Ectopic Gem expression is sufficient to stimulate cell flattening and neurite extension in N1E-115 and SH-SY5Y neuroblastoma cells, Gem was also observed in developing trigeminal nerve ganglia in 12, High intracellular Gem levels, Rad and Gem bind calmodulin in a Ca2+-dependent manner via this C-terminal extension, The human Gem gene maps to chromosome &, The interaction of Gem with beta-subunits regulates Ca2+ channel expression at the cell surface, demonstrating that Gem expression is a property of normal ganglionic development, involving residues 278â, promote profound changes in cell morphology, suggesting a role for Gem in cytoskeletal rearrangement and/or morphological differentiation of neurons, which interact with intact microtubules and microfilaments, which lack typical C-terminal amino acid motifs for isoprenylation, #65279, &euro, &ldquo, 1, 297 in human Rad, 5 day mouse embryos, 8q22, Gem belongs to the Rad/Gem/Kir (RGK) subfamily of Ras-related GTPases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
KIR |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GEM Conjugated |
| Short name: |
Conjugated, GEM Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GEM (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4234 |
| Gene: |
GEM |
More about : GEM |
| Long gene name: |
GTP binding protein overexpressed in skeletal muscle |
| Synonyms gene name: |
GTP-binding protein overexpressed in skeletal muscle |
| Synonyms name: |
kinase-inducible Ras-like protein |
| Locus: |
8q22, 1 |
| Discovery year: |
1995-08-15 |
| Entrez gene record: |
2669 |
| Pubmed identfication: |
7912851 11956230 |
| RefSeq identity: |
NM_181702 |
| Classification: |
RGK type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000164392 |