| Long name: |
GEM Primary Polyclonal Antibody |
| Also known as: |
GEM PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GEM |
| Specificity: |
This is a highly specific antibody against GEM |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GEM |
| Gene ID number: |
2669 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Ectopic Gem expression is sufficient to stimulate cell flattening and neurite extension in N1E-115 and SH-SY5Y neuroblastoma cells, Gem was also observed in developing trigeminal nerve ganglia in 12, High intracellular Gem levels, Rad and Gem bind calmodulin in a Ca2+-dependent manner via this C-terminal extension, The human Gem gene maps to chromosome &, The interaction of Gem with beta-subunits regulates Ca2+ channel expression at the cell surface, demonstrating that Gem expression is a property of normal ganglionic development, involving residues 278â, promote profound changes in cell morphology, suggesting a role for Gem in cytoskeletal rearrangement and/or morphological differentiation of neurons, which interact with intact microtubules and microfilaments, which lack typical C-terminal amino acid motifs for isoprenylation, #65279, &euro, &ldquo, 1, 297 in human Rad, 5 day mouse embryos, 8q22, Gem belongs to the Rad/Gem/Kir (RGK) subfamily of Ras-related GTPases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GEM_HUMAN, GTP binding protein GEM, GTP binding protein expressed in mitogen stimulated T cells, GTP binding protein overexpressed in skeletal muscle, KIR, Kinase inducible Ras like protein, MGC26294, RAS like protein KIR, GTP binding mitogen induced T cell protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GEM |
| Short name: |
GEM Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GEM (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4234 |
| Gene: |
GEM |
More about : GEM |
| Long gene name: |
GTP binding protein overexpressed in skeletal muscle |
| Synonyms gene name: |
GTP-binding protein overexpressed in skeletal muscle |
| Synonyms: |
KIR |
| Synonyms name: |
kinase-inducible Ras-like protein |
| Locus: |
8q22, 1 |
| Discovery year: |
1995-08-15 |
| Entrez gene record: |
2669 |
| Pubmed identfication: |
7912851 11956230 |
| RefSeq identity: |
NM_181702 |
| Classification: |
RGK type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000164392 |