| Long name: |
Biotin Conjugated, FDPS Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FDPS |
| Specificity: |
This is a highly specific antibody against FDPS |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FDPS |
| Gene ID number: |
2224 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Existing as a homodimer, FDPS assists in cholesterol biosynthesis, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids, FDPS is inactivated by interferon-induced RSAD2, FDPS may have anti-viral effects when inactivated by RSAD2, Localized to cytoplasm and peroxisome, Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, a precursor for several classes of essential metabolites including sterols, and ubiquinones, both of which are known to be peroxisomal deficiency diseases, carotenoids, dolichols, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway, which may result in the disruption of lipid rafts at the plasma membrane, FDPS catalyzes the formation of farnesyl diphosphate (FPP), FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FDPS Conjugated |
| Short name: |
Conjugated, FDPS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, FDPS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3631 |
| Gene: |
FDPS |
More about : FDPS |
| Long gene name: |
farnesyl diphosphate synthase |
| Synonyms name: |
dimethylallyltranstransferase, farnesyl pyrophosphate synthetase, geranyltranstransferase |
| Locus: |
1q22 |
| Discovery year: |
1992-03-13 |
| GenBank acession: |
J05262 |
| Entrez gene record: |
2224 |
| Pubmed identfication: |
1968462 |
| RefSeq identity: |
NM_002004 |
| Havana BLAST/BLAT: |
OTTHUMG00000013909 |