| Long name: |
FDPS Primary Polyclonal Antibody |
| Also known as: |
FDPS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FDPS |
| Specificity: |
This is a highly specific antibody against FDPS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FDPS |
| Gene ID number: |
2224 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Existing as a homodimer, FDPS assists in cholesterol biosynthesis, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids, FDPS is inactivated by interferon-induced RSAD2, FDPS may have anti-viral effects when inactivated by RSAD2, Localized to cytoplasm and peroxisome, Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, a precursor for several classes of essential metabolites including sterols, and ubiquinones, both of which are known to be peroxisomal deficiency diseases, carotenoids, dolichols, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway, which may result in the disruption of lipid rafts at the plasma membrane, FDPS catalyzes the formation of farnesyl diphosphate (FPP), FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
6E-farnesyl diphosphate synthase, Dimethylallyltranstransferase, FPP synthase, FPP synthetase, FPPS, FPPS_HUMAN, FPS, Farnesyl diphosphate synthase, Farnesyl diphosphate synthetase, Farnesyl pyrophosphate synthase, Farnesyl pyrophosphate synthetase, Fdps, Geranyltranstransferase, 2E, 6E farnesyl diphosphate synthase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FDPS |
| Short name: |
FDPS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FDPS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3631 |
| Gene: |
FDPS |
More about : FDPS |
| Long gene name: |
farnesyl diphosphate synthase |
| Synonyms name: |
dimethylallyltranstransferase, farnesyl pyrophosphate synthetase, geranyltranstransferase |
| Locus: |
1q22 |
| Discovery year: |
1992-03-13 |
| GenBank acession: |
J05262 |
| Entrez gene record: |
2224 |
| Pubmed identfication: |
1968462 |
| RefSeq identity: |
NM_002004 |
| Havana BLAST/BLAT: |
OTTHUMG00000013909 |