| Long name: |
ALEXA FLUOR 350 Conjugated, FDPS Polyclonal Antibody |
| Also known as: |
Anti-FDPS PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FDPS |
| Specificity: |
This is a highly specific antibody against FDPS |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FDPS |
| Gene ID Number: |
2224 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Existing as a homodimer, FDPS assists in cholesterol biosynthesis, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids, FDPS is inactivated by interferon-induced RSAD2, FDPS may have anti-viral effects when inactivated by RSAD2, Localized to cytoplasm and peroxisome, Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, a precursor for several classes of essential metabolites including sterols, and ubiquinones, both of which are known to be peroxisomal deficiency diseases, carotenoids, dolichols, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway, which may result in the disruption of lipid rafts at the plasma membrane, FDPS catalyzes the formation of farnesyl diphosphate (FPP), FDPS is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
FDPS |
| Short name: |
FDPS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, FDPS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3631 |
| Gene: |
FDPS |
More about : FDPS |
| Long gene name: |
farnesyl diphosphate synthase |
| Synonyms name: |
dimethylallyltranstransferase, farnesyl pyrophosphate synthetase, geranyltranstransferase |
| Locus: |
1q22 |
| Discovery year: |
1992-03-13 |
| GenBank acession: |
J05262 |
| Entrez gene record: |
2224 |
| Pubmed identfication: |
1968462 |
| RefSeq identity: |
NM_002004 |
| Havana BLAST/BLAT: |
OTTHUMG00000013909 |