| Long name: |
Cy3 Conjugated, ASAH1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASAH1 |
| Specificity: |
This is a highly specific antibody against ASAH1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Acid ceramidase subunit beta |
| Gene ID number: |
427 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma, Effected individuals experience early onset joint problems and neurological problems, In addition to ceramide hydrolysis, Interestingly, a hallmark of Farber disease, and deficiency leads to accumulation of ceramide in tissues, for hydrolysis the pH optimum is 4, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism, owing to mutations in the acid ceramidase gene, pH regulates which reaction is favored, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates, whereas for the reverse reaction favors a pH of 5, 5, 5, Acid ceramidase catalyzes the degradation of ceramide in normal tissues |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
AC PHP32 FLJ21558 ACDase |
| Properties: |
1 of the ASAH1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ASAH1 Conjugated |
| Short name: |
Conjugated, ASAH1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, ASAH1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
735 |
| Gene: |
ASAH1 |
More about : ASAH1 |
| Long gene name: |
N-acylsphingosine amidohydrolase 1 |
| Synonyms gene: |
ASAH |
| Synonyms gene name: |
N-acylsphingosine amidohydrolase (acid ceramidase) |
| Synonyms name: |
acylsphingosine deacylase acid ceramidase |
| Locus: |
8p22 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U70063 |
| Entrez gene record: |
427 |
| Pubmed identfication: |
8955159 10610716 |
| RefSeq identity: |
NM_004315 |
| Havana BLAST/BLAT: |
OTTHUMG00000096997 |