| Long name: |
ALEXA FLUOR 555 Conjugated, ASAH1 Polyclonal Antibody |
| Also known as: |
Anti-ASAH1 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ASAH1 |
| Specificity: |
This is a highly specific antibody against ASAH1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acid ceramidase subunit beta |
| Gene ID Number: |
427 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma, Effected individuals experience early onset joint problems and neurological problems, In addition to ceramide hydrolysis, Interestingly, a hallmark of Farber disease, and deficiency leads to accumulation of ceramide in tissues, for hydrolysis the pH optimum is 4, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism, owing to mutations in the acid ceramidase gene, pH regulates which reaction is favored, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates, whereas for the reverse reaction favors a pH of 5, 5, 5, Acid ceramidase catalyzes the degradation of ceramide in normal tissues |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
AC PHP32 FLJ21558 ACDase |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
ASAH1 |
| Short name: |
ASAH1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, ASAH1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
735 |
| Gene: |
ASAH1 |
More about : ASAH1 |
| Long gene name: |
N-acylsphingosine amidohydrolase 1 |
| Synonyms gene: |
ASAH |
| Synonyms gene name: |
N-acylsphingosine amidohydrolase (acid ceramidase) |
| Synonyms name: |
acylsphingosine deacylase acid ceramidase |
| Locus: |
8p22 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
U70063 |
| Entrez gene record: |
427 |
| Pubmed identfication: |
8955159 10610716 |
| RefSeq identity: |
NM_004315 |
| Havana BLAST/BLAT: |
OTTHUMG00000096997 |