| Long name: |
ALEXA FLUOR 647 Conjugated, ARP2/ARP3 Polyclonal Antibody |
| Also known as: |
Anti-ARP2/ARP3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ARP2/ARP3 |
| Specificity: |
This is a highly specific antibody against ARP2/ARP3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARP2/ARP3 |
| Gene ID Number: |
10097 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, In addition, In response to GTP-binding Cdc42, The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, and initiates the formation of lamellipodia and filopodia, and nucleates growth in the barbed direction, and platelet activation, and various other accessory proteins, cell adhesion, cell migration, including chemotaxis, namely the WASP proteins, or by associating with the side of an existing filament, or the uncapping of existing barbed ends, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases, the Arp2/3 complex binds the Cdc42 substrates, the severing of existing filaments to create uncapped barbed ends, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork, Actin polymerization is required for a variety of cell functions |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
ARP2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ARP2/ARP3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ARP2/ARP3 |
| Short name: |
ARP2/ARP3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ARP2/ARP3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
169 |
| Gene: |
ACTR2 |
More about : ACTR2 |
| Long gene name: |
ARP2 actin related protein 2 homolog |
| Synonyms gene name: |
ARP2 (actin-related protein 2, yeast) homolog ARP2 actin-related protein 2 homolog (yeast) |
| Locus: |
2p14 |
| Discovery year: |
1999-05-17 |
| GenBank acession: |
AF006082 |
| Entrez gene record: |
10097 |
| Pubmed identfication: |
9230079 |
| RefSeq identity: |
NM_001005386 |
| Classification: |
Actin related protein 2/3 complex |
| Havana BLAST/BLAT: |
OTTHUMG00000129540 |