ARP2/ARP3 Antibody, ALEXA FLUOR 555

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Catalog number: bs-12524R-A555
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: ARP2/ARP3 Antibody, ALEXA FLUOR 555
Quantity: 0.1ml
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Long name: ALEXA FLUOR 555 Conjugated, ARP2/ARP3 Polyclonal Antibody
Also known as: Anti-ARP2/ARP3 PAb ALEXA FLUOR 555
Category: Conjugated Primary Antibodies
Conjugated with: 555, ALEXA FLUOR®
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: ARP2/ARP3
Specificity: This is a highly specific antibody against ARP2/ARP3
Modification: Unmodified
Modification Site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARP2/ARP3
Gene ID Number: 10097
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Mouse, Rat, Human
Cross-reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen: Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, In addition, In response to GTP-binding Cdc42, The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, and initiates the formation of lamellipodia and filopodia, and nucleates growth in the barbed direction, and platelet activation, and various other accessory proteins, cell adhesion, cell migration, including chemotaxis, namely the WASP proteins, or by associating with the side of an existing filament, or the uncapping of existing barbed ends, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases, the Arp2/3 complex binds the Cdc42 substrates, the severing of existing filaments to create uncapped barbed ends, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork, Actin polymerization is required for a variety of cell functions
Purification: Purified by Protein A
Storage conditions: 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission: 553nm/568nm
Synonyms: ARP2
Properties: ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation: ALEXA FLUOR 555, Alexa Fluor
Gene target: ARP2/ARP3
Short name: ARP2/ARP3 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Label: ALEXA FLUOR 555
Alternative name: ALEXA FLUOR 555, ARP2/ARP3 (Antibody to)
Alternative technique: antibodies
Identity: 169
Gene: ACTR2 | More about : ACTR2
Long gene name: ARP2 actin related protein 2 homolog
Synonyms gene name: ARP2 (actin-related protein 2, yeast) homolog ARP2 actin-related protein 2 homolog (yeast)
Locus: 2p14
Discovery year: 1999-05-17
GenBank acession: AF006082
Entrez gene record: 10097
Pubmed identfication: 9230079
RefSeq identity: NM_001005386
Classification: Actin related protein 2/3 complex
Havana BLAST/BLAT: OTTHUMG00000129540

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