| Long name: |
FITC Conjugated, AOA1/Aprataxin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AOA1/Aprataxin |
| Specificity: |
This is a highly specific antibody against AOA1/Aprataxin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human AOA1/Aprataxin |
| Gene ID number: |
54840 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ20157 AOA AOA1 EAOH EOAHA |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AOA1/Aprataxin Conjugated |
| Short name: |
FITC Conjugated, AOA1/Aprataxin Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, AOA1/Aprataxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15984 |
| Gene: |
APTX |
More about : APTX |
| Long gene name: |
aprataxin |
| Synonyms gene: |
AXA1 |
| Synonyms gene name: |
ataxia 1, early onset with hypoalbuminemia |
| Locus: |
9p21, 1 |
| Discovery year: |
2001-07-16 |
| GenBank acession: |
AK000164 |
| Entrez gene record: |
54840 |
| Pubmed identfication: |
11586299 11586300 |
| RefSeq identity: |
NM_017692 |
| Havana BLAST/BLAT: |
OTTHUMG00000019759 |