| Catalog number: | bs-12504R-A350 |
|---|---|
| Price: | 1757 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | AOA1/Aprataxin Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ug |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, AOA1/Aprataxin Polyclonal Antibody |
|---|---|
| Also known as: | Anti-AOA1/Aprataxin PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | AOA1/Aprataxin |
| Specificity: | This is a highly specific antibody against AOA1/Aprataxin |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AOA1/Aprataxin |
| Gene ID Number: | 54840 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | FLJ20157 AOA AOA1 EAOH EOAHA |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | AOA1/Aprataxin |
| Short name: | AOA1/Aprataxin Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, AOA1/Aprataxin (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 15984 |
| Gene: | APTX | More about : APTX |
| Long gene name: | aprataxin |
| Synonyms gene: | AXA1 |
| Synonyms gene name: | ataxia 1, early onset with hypoalbuminemia |
| Locus: | 9p21, 1 |
| Discovery year: | 2001-07-16 |
| GenBank acession: | AK000164 |
| Entrez gene record: | 54840 |
| Pubmed identfication: | 11586299 11586300 |
| RefSeq identity: | NM_017692 |
| Havana BLAST/BLAT: | OTTHUMG00000019759 |
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