| Long name: |
AOA1/Aprataxin Primary Polyclonal Antibody |
| Also known as: |
AOA1/Aprataxin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AOA1/Aprataxin |
| Specificity: |
This is a highly specific antibody against AOA1/Aprataxin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AOA1/Aprataxin |
| Gene ID number: |
54840 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AOA, AOA, AOA1, AOA1, APTX, APTX, APTX_HUMAN, AXA 1, AXA1, AXA1, Aprataxin, Aprataxin, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, EAOH, EAOH, EOAHA, EOAHA, FHA HIT, FHA HIT, FHA-HIT, FLJ20157, FLJ20157, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein, Forkhead-associated domain histidine triad-like protein, MGC1072, MGC1072, AOA 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AOA1/Aprataxin |
| Short name: |
AOA1/Aprataxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AOA1/Aprataxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15984 |
| Gene: |
APTX |
More about : APTX |
| Long gene name: |
aprataxin |
| Synonyms gene: |
AXA1 |
| Synonyms gene name: |
ataxia 1, early onset with hypoalbuminemia |
| Synonyms: |
FLJ20157 AOA AOA1 EAOH EOAHA |
| Locus: |
9p21, 1 |
| Discovery year: |
2001-07-16 |
| GenBank acession: |
AK000164 |
| Entrez gene record: |
54840 |
| Pubmed identfication: |
11586299 11586300 |
| RefSeq identity: |
NM_017692 |
| Havana BLAST/BLAT: |
OTTHUMG00000019759 |