| Long name: |
ALEXA FLUOR 647 Conjugated, AOA1/Aprataxin Polyclonal Antibody |
| Also known as: |
Anti-AOA1/Aprataxin PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AOA1/Aprataxin |
| Specificity: |
This is a highly specific antibody against AOA1/Aprataxin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AOA1/Aprataxin |
| Gene ID Number: |
54840 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, Aprataxin is involved in DNA single-strand break repair, Loss of function mutations in APTX, These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain, characterized by abnormal movements of the head and eyes, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, mediating protein-protein interactions with molecules responding to DNA damage, present in both the nucleoplasm and the nucleolus, the gene encoding for Aprataxin, which is a member of the histidine triad (HIT) superfamily, Aprataxin is a nuclear protein |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
FLJ20157 AOA AOA1 EAOH EOAHA |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the AOA1/Aprataxin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
AOA1/Aprataxin |
| Short name: |
AOA1/Aprataxin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, AOA1/Aprataxin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15984 |
| Gene: |
APTX |
More about : APTX |
| Long gene name: |
aprataxin |
| Synonyms gene: |
AXA1 |
| Synonyms gene name: |
ataxia 1, early onset with hypoalbuminemia |
| Locus: |
9p21, 1 |
| Discovery year: |
2001-07-16 |
| GenBank acession: |
AK000164 |
| Entrez gene record: |
54840 |
| Pubmed identfication: |
11586299 11586300 |
| RefSeq identity: |
NM_017692 |
| Havana BLAST/BLAT: |
OTTHUMG00000019759 |