APC10 Antibody, Cy5 Conjugated

Catalog number:	bs-12483R-Cy5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	APC10 Antibody, Cy5 Conjugated
Quantity:	0.1ml
Related search:	apc antibody antibodies conjugated gene complex cdc term

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Long name:	Cy5 Conjugated, APC10 Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	APC10
Specificity:	This is a highly specific antibody against APC10
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from human APC10
Gene ID number:	10393
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	APC, APC is phosphorylated, APC is under tight control by a number of regulatory factors, APC10 also localizes to kinetochores from prophase to anaphase, APC10 binds to core APC subunits throughout the cell cycle, APC10 binds to the C-terminus of CDC27/APC3, APC10 contains a Doc1 homology domain, APC10 is localized in centrosomes and mitotic spindles, CDC20 and CDH1 directly bind to and activate the cyclin-ubiquitination activity of APCs, CDH1 and MAD2, During mitosis, In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, Specifically, Specifically, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division, and thus activated, and to the midbody in telophase and cytokinesis, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk), including CDC20, or cyclosome, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis, thus preventing APC activation, which is a beta-sandwich structure common to many other putative E3 ubiquitin ligases, Composed of more than ten subunits
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	APC10 DOC1 DKFZP564L0562
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	APC10 Conjugated
Short name:	Conjugated, APC10 Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, APC10 (Antibody to)
Alternative technique:	antibodies
Identity:	24077
Gene:	ANAPC10 | More about : ANAPC10
Long gene name:	anaphase promoting complex subunit 10
Locus:	4q31, 21
Discovery year:	2004-05-21
GenBank acession:	AF132794
Entrez gene record:	10393
Pubmed identfication:	10318877 11230166
RefSeq identity:	NM_014885
Classification:	Anaphase promoting complex
Havana BLAST/BLAT:	OTTHUMG00000161477

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